Lamellar bodies in heterotopic neurons of the cerebellum
SummarySmall eosinophilic inclusion bodies were observed in the cytoplasm and processes of heterotopic neurons of the cerebellum in a case of Werdnig-Hoffmann disease. They were oval, triangular, or...
View ArticleImmunohistochemical localization of neurofilament protein in neuronal...
SummaryThe immunohistochemical localization of human neurofilament proteins was studied in a variety of neuronal changes by the peroxidase-antiperoxidase method using antisera raised against each of...
View ArticleImmunohistochemical study of the early human fetal brain
SummaryTo assess the cytogenesis of the central nervous system we studied the spinal cord and the cerebrum in 11 human embryos and fetuses of gestation age 7–25 weeks immunohistochemically using...
View ArticleDiffuse type of senile plaques in the cerebellum of Alzheimer-type dementia...
SummaryWe studied senile plaques (SP) in the cerebella of six autopsied subjects with Alzheimer-type dementia (ATD) and ten non-ATD autopsied subjects between the ages of 78 and 90. Neither SP nor...
View ArticleDistinctive, rapid, and easy labeling of diffuse plaques in the Alzheimer...
SummaryWe have developed a new methenamine silver (MS) stain for detecting diffuse plaques distinctively on paraffin-embedded tissue sections of Alzheimer-type dementia, Down'n syndrome, and mentally...
View ArticleUltrastructure of the neuropil threads in the Alzheimer brain: their...
SummaryThread-like structures immunoreactive with paired helical filaments and tau antisera were demonstrated as mesh-works in the neocortices of five brains with Alzheimer-type dementia, but not in...
View ArticleExtracellular neurofibrillary tangles associated with degenerating neurites...
SummaryWe examined the cellular components of extracellular neurofibrillary tangles (E-NFT) in the hippocampal areas in cases with Alzheimer-type dementia. Immunohistochemically, the E-NFT were labeled...
View ArticleUltrastructure of diffuse plaques in senile dementia of the Alzheimer type:...
SummaryWe compared the ultrastructure between diffuse and primitive plaques in the brains of senile dementia, using pairs of routine electron microscopic ultrathin sections and adjacent semithin...
View ArticleFatal outcome of a patient with severe aplastic anemia after treatment with...
SummaryA 75-year-old man suffering from severe aplastic anemia was treated first with cyclosporin A, then with stereoid pulse therapy, and subsequently with metenolone acetate. Marked elevation of...
View ArticleCalcium channel subtypes in porcine adrenal chromaffin cells
Abstract The effects of nifedipine, ω-conotoxin GVIA (ω-CgTx) and ω-agatoxin IVA (ω-AgTx) on Ca2+ currents, a 60-mM-K+-induced increase in intracellular Ca2+ concentration ([Ca2+]i) and catecholamine...
View ArticleCalcium channel current facilitation in porcine adrenal chromaffin cells
Abstract The mechanisms of depolarizing-prepulse-induced facilitation of Ca2+ channel current were investigated in a study of porcine chromaffin cells. The Ba2+ current evoked by a pulse to 0 mV was...
View ArticleTwo autopsy cases with Pelizaeus-Merzbacher disease phenotype of adult onset,...
Abstract We report the autopsy cases of two brothers which are pathologically compatible with Pelizaeus-Merzbacher disease (PMD). Both patients had a late onset (at the ages of 29 and 42 years) and...
View ArticleFragmentation of the Golgi apparatus of the ballooned neurons in patients...
Abstract We investigated immunohistologically the Golgi apparatus (GA) and the trans-Golgi network (TGN) of the cortical ballooned neurons (BNs) in two patients with corticobasal degeneration and in...
View ArticleCalcified Vestibular Schwannoma with Unusual Histological Characteristics –...
Summary. Calcification in vestibular schwannoma is extremely rare. A 36-year-old man presented with a history of decreased hearing on the left since childhood. Computed tomography showed a left...
View ArticleA case of germinoma in the septum pellucidum manifesting as amnesia and...
Summary¶Background. We report a rare case of germinoma mainly located in the septum pellucidum.Case description. A 19-year-old man presented with germinoma located in the septum pellucidum manifesting...
View ArticleMicromanipulation system using scanning electron microscope
AbstractIn this study, we aimed to develop a micromechanism in which constituent parts of μm order are used and to establish the handling technology required to achieve this. On the basis of the...
View ArticleDevelopment of In-Pipe Micro Mobile Robot Using Peristalsis Motion Driven by...
AbstractIn this paper, we developed an in-pipe mobile robot which operates in the blood vessels. For this purpose, the diameter of the robot was designed to be equivalent to or smaller than that of...
View ArticleDevelopment of Peristaltically Propelled Active Catheter Used in Radial Artery
AbstractIn our previous studies, many experiments using pseudoblood vessels with an inner diameter of ≤6 mm have been carried out assuming that the catheter is inserted in a femoral artery. In recent...
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